Running the following commands will fix the XenCenter Error. You are typically encountering this error because Windows 10 requires stronger encryption, consequently, this is prevalent on older XenServer installations. I encountered this on XenServer 6.0.
service xapissl stop mv /etc/xensource/xapi-ssl.pem /etc/xensource/xapi-ssl.pem.bak /opt/xensource/libexec/generate_ssl_cert "/etc/xensource/xapi-ssl.pem" '10.100.0.40' service xapissl start xe-toolstack-restart
Where you see 10.100.0.40 this is the IP of your XenServer that you are connecting to (not VM ips). Once you run this it reissues the cert and you will be able to properly connect. I’ve seen this on Windows 10 Systems since they force the higher level encryption, however, If this doesn’t resolve the XenCenter error let me know.